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Z-VRPR-FMK trifluoroacetate salt

CAS No. ——

Z-VRPR-FMK trifluoroacetate salt( —— )

Catalog No. M30776 CAS No. ——

Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Z-VRPR-FMK trifluoroacetate salt
  • Note
    Research use only, not for human use.
  • Brief Description
    Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
  • Description
    Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    790.81
  • Molecular Formula
    C31H49FN10O6.CF3CO2H
  • Purity
    >98% (HPLC)
  • Solubility
    water with gentle warming:1 mg/mL
  • SMILES
    OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C(=O)CF
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rebeaud et al (2008) The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat.Immunol. 9 272 PMID:
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